nucleotide binding site/leucine-rich repeat genes

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A large group of plant disease resistance genes (nbs-lrr genes) which also mediate pathogen recognition in animals. Two major subclasses are the tir-nbs-lrr genes that encode proteins with similarity to toll and interleukin-1 receptors, while the non-TIR class typically contains a coiled-coil (CC) domain in the N-terminal region.

Subjects: Medicine and Health.

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