'ouabain' can also refer to...





Ouabain and hypertension.

317 Ouabain-like factor production in control and ischemic heart

Plasma marinobufagenin-like and ouabain-like immunoreactivity during saline volume expansion in anesthetized dogs

Independent and incremental prognostic value of endogenous ouabain in idiopathic dilated cardiomyopathy

Ouabain triggers preconditioning through activation of the Na+,K+-ATPase signaling cascade in rat hearts

Endogenous ouabain and hemodynamic and left ventricular geometric patterns in essential hypertension

A new clinical multivariable model that predicts postoperative acute kidney injury: impact of endogenous ouabain

Increased circulating levels of ouabain-like factor in patients with asymptomatic left ventricular dysfunction

Effects of a Na+/Ca2+ exchanger inhibitor on pulmonary vein electrical activity and ouabain-induced arrhythmogenicity

Gingerol, isoproterenol and ouabain normalize impaired post-rest behavior but not force–frequency relation in failing human myocardium

DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase

Lithium and Tamoxifen Modulate Behavior and Protein Kinase C Activity in the Animal Model of Mania Induced by Ouabain

A fourth class of anti-dysrhythmic action? Effect of verapamil and ouabain toxicity, on atrial and ventricular intracellular potentials, and on other features of cardiac function

The mutagenic response at the ouabain resistance locus in T cells of mice exposed to N-ethyl-N-nitrosourea parallels the response at the Hprt locus and correlates with mutation target size.


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A toxic glycoside derived from the seeds of certain African plants, such as Strophanthus gratus, that has been used historically as a drug to stimulate contractions of heart muscle in treating heart failure and other conditions. It specifically blocks the action of sodium/potassium ATPase (see sodium pump), a crucial membrane-bound transport protein that maintains differential ion concentrations between a cell's interior and the external environment. For this property, ouabain is used widely in biomedical research, and it is now known to occur naturally in the body at very low concentrations.

Subjects: Biological Sciences — Chemistry.

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