Overview

ovalocytosis


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Hereditary disorder of erythrocytes relatively common in areas where malaria is endemic. Not only are the erythrocytes more rigid, but there is a mutation in band III, the anion transporter. Other forms, such as hereditary haemolytic ovalocytosis, may be caused by mutation in other genes involved in maintaining erythrocyte shape and known to be associated with elliptocytosis: band III, spectrin, protein 4.1, or protein 4.2.

Subjects: Medicine and Health — Chemistry.


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