Overview

pannexins


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A family of a widely expressed proteins (~45 kDa) with structural, but not amino acid, homology with gap junction proteins, the connexins. Pannexin 1 does not form gap junctions but it forms mechanosensitive ATP-permeable channels in erythrocytes. There are three isoforms (pannexins 1–3) which have different distributions.

Subjects: Medicine and Health.


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