Overview

PARP-1


'PARP-1' can also refer to...

PARP‐1

Update on PARP1 inhibitors in ovarian cancer

ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells

PARP-2 and PARP-3 are selectively activated by 5′ phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1

PARP1 is required for adhesion molecule expression in atherogenesis

PARP-1 regulates epithelial–mesenchymal transition (EMT) in prostate tumorigenesis

PARP1 suppresses homologous recombination events in mice in vivo

Visualization of a DNA-PK/PARP1 complex

BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability

PARP-1 cooperates with Ptc1 to suppress medulloblastoma and basal cell carcinoma

PARP1–TDP1 coupling for the repair of topoisomerase I–induced DNA damage

O6.1Classification of PARP inhibitors based on PARP trapping and catalytic inhibition, and rationale for combinations

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

Nuclear PARP-1 protein overexpression is associated with poor overall survival in early breast cancer

PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies

PARP-1 suppresses adiponectin expression through poly(ADP-ribosyl)ation of PPARγ in cardiac fibroblasts

PARP1 ADP-ribosylates lysine residues of the core histone tails

ARF induction in response to DNA strand breaks is regulated by PARP1

Poly(ADP‐ribose) polymerase (PARP‐1) has a controlling role in homologous recombination

 

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abbr. for poly(ADP‐ribose) polymerase 1; in mammals, a highly conserved protein (113 kDa) that is strongly activated by DNA strand breaks, and participates in modulating DNA base excision repair, apoptosis ...

Subjects: Chemistry.


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