A paternally expressed gene required for normal fertilization and early embryonic development. Males homozygous for recessive alleles of such genes produce sperm that cannot support normal development in the embryo, even if the egg is from a female that is homozygous for the wild-type allele, while the reciprocal cross (i.e., wild-type male × homozygous recessive female) produces viable embryos. The genotype of the father thus affects the phenotype of his offsprings. Compare with maternal effect gene, zygotic gene.
Subjects: Genetics and Genomics.