Overview

peptide nucleic acid


'peptide nucleic acid' can also refer to...

peptide nucleic acid

peptide nucleic acid

Strand invasion by DNA-peptide conjugates and peptide nucleic acids

Peptide Nucleic Acids as Prebiotic and Abiotic Genetic Material

Inhibition of a DNA-helicase by peptide nucleic acids

DNA assembly using bis-peptide nucleic acids (bisPNAs)

Hybridisation based DNA screening on peptide nucleic acid (PNA) oligomer arrays

Synthesis and characterization of new chiral peptide nucleic acid (PNA) monomers

Synthesis of oxy-peptide nucleic acids with mixed sequences

Control of electron transfer in DNA by peptide nucleic acids (PNA)

Advantages of peptide nucleic acids as diagnostic platforms for detection of nucleic acids in resource-limited settings

Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs)

Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs)

The peptide nucleic acids: a new way for chromosomal investigation on isolated cells?

End invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes

End invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids

On the stability of peptide nucleic acid duplexes in the presence of organic solvents

 

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(PNA)

A synthetic analogue of nucleic acid, in which the sugar-phosphate backbone is replaced by a peptide-like polyamide. PNAs will bind to complementary DNA or RNA and are resistant to both nucleases and peptidases. Extensively used as experimental tools, but early optimism about their potential therapeutic uses has diminished.

Subjects: Medicine and Health.


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