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peptidyl prolyl cis/trans-isomerases


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Enzymes (PPIases, EC 5.2.1.8) that catalyse the cis–trans isomerization of prolyl bonds in oligopeptides, an important factor in correct protein folding. The prolyl isomerase activity is apparently unimportant for the immunosuppressive role of the immunophilins. Parvulins also have PPIase activity.

Subjects: Medicine and Health.


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