periventricular leucomalacia

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(PVL) softening of white matter around the ventricles of the brain in preterm infants due to a decreased blood supply to the brain, usually associated with hypoxic-ischaemic encephalopathy. Diagnosis is by ultrasound, which shows increased density and, later, cysts in the periventricular area. The brain damage can cause visual impairment and cerebral palsy.

Subjects: Medicine and Health.

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