A gene conferring resistance in mosquitoes to the insecticide chloroquine (q.v.). The acronym stands for “P lasmodium f alciparum chloroquine- resistance transporter,” and the gene encodes a transmembrane protein of the food vacuole of the merozoite (q.v.). Mutations in this protein reduce uptake of the insecticide. See vacuoles.
Subjects: Genetics and Genomics.