phorbol ester

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phorbol ester

phorbol esters

Phorbol Ester-Potentiated Liposomal Transfection to Monocytic PLB-985 Cells

Phorbol Ester, but Not Endotoxin, Desensitizes Mannan-Induced Glycogenolysis in the Perfused Rat Liver

Phorbol Ester Facilitates Apoptosis in Murine Fibroblasts Pretreated by Mild Ultraviolet Radiation

Diversity and similarity in signaling events leading to rapid Cox-2 induction by tumor necrosis factor-α and phorbol ester in human endothelial cells

Shiga Toxin Induces Superoxide Production in Polymorphonuclear Cells with Subsequent Impairment of Phagocytosis and Responsiveness to Phorbol Esters

Two Distinct Mechanisms Underlie the Stimulation of Neurotransmitter Release by Phorbol Esters in Clonal Rat Phechromocytoma PC12 Cells

Recovery of gap junctional intercellular communication after phorbol ester treatment requires proteasomal degradation of protein kinase C

Suppression by citrus auraptene of phorbol ester- and endotoxin-induced inflammatory responses: role of attenuation of leukocyte activation

Phorbol ester-induced production of cytostatic factors by normal and oncogenic Ha-ras-transformed human breast cell lines

Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells

Effects of protein kinase C activators on phorbol ester-sensitive and -resistant EL4 thymoma cells.

Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin

Inhibition of phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate-caused inflammatory responses in SENCAR mouse skin by black tea polyphenols.

Transepithelial paracellular leakiness induced by chronic phorbol ester exposure correlates with polyp-like foci and redistribution of protein kinase C-alpha.

Phorbol ester effects on splenic lymphocyte composition and cytotoxic T cell activities of SSIN mice: a strain deficient in CD8+ T cells

Phorbol esters and synthetic diacylglycerols inhibit gamma-aminobutyric acid uptake in human spermatozoa: an effect mediated by protein kinase C?

hMSH2 expression is driven by AP1‐dependent regulation through phorbol‐ester exposure


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Quick Reference

A range of polycyclic compounds isolated from croton oil (from the seeds of Croton tigliumin), the commonest of which is phorbol myristoyl acetate (PMA). They are potent cocarcinogens or tumour promotors, acting as diacyl glycerol analogues to irreversibly activate protein kinase C.

Subjects: Chemistry.

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