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phyllolitorin


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A bombesin-like peptide, originally isolated from the skin of the South American frog Phyllomedusa sauvagei. The precursor peptide (90 aa) has a signal sequence, and the 9-aa phyllolitorin peptide flanked by N- and C-terminal extension peptides. Leu8-phyllolitorin increases branching of developing airways. Central injection of Leu8-phyllolitorin has been shown to produce hypothermia in animals exposed to a cold environment.

Subjects: Medicine and Health.


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