A bombesin-like peptide, originally isolated from the skin of the South American frog Phyllomedusa sauvagei. The precursor peptide (90 aa) has a signal sequence, and the 9-aa phyllolitorin peptide flanked by N- and C-terminal extension peptides. Leu8-phyllolitorin increases branching of developing airways. Central injection of Leu8-phyllolitorin has been shown to produce hypothermia in animals exposed to a cold environment.
Subjects: Medicine and Health.