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A cell-permeable ATP competitor that selectively inhibits DNA-activated protein kinase, PI-3-kinase, the rapamycin-sensitive (mTORC1), and rapamycin-insensitive (mTORC2) complexes of the protein kinase mTOR, but has little activity against a range of other kinases. Blocks cell proliferation in glioma cell lines both in vitro and in vivo.

Subjects: Medicine and Health.

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