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pim


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A family of oncogenes that encode serine/threonine protein kinases. Pim-1 (404 aa) is up-regulated in prostate cancer; pim-2 (334 aa) is highly expressed in human leukaemic and lymphoma cell lines and a colorectal adenocarcinoma cell line; pim-3 (326 aa) is aberrantly expressed in human pancreatic cancer and phosphorylates bad.

Subjects: Chemistry — Medicine and Health.


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