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A type I membrane glycoprotein (T1A, aggrus, OTS8, GP36, 162 aa) that is a marker for normal lymphatic endothelial cells, although expression is increased in many intestinal tumours. Can be detected immunochemically by the monoclonal antibody D2-40 and is a potential tumour marker. One domain has platelet-aggregating properties and is involved in tumour cell-induced platelet aggregation.

Subjects: Medicine and Health.

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