1. a mutant gene that is able to reduce the rate of synthesis of the proteins that normally would be produced by wild-type alleles of the genes lying beyond it on the chromosome. Such genes exert their effect during the translation of a polycistronic message (q.v.). See regulator gene, translation. 2. a mutant gene that influences polarized patterns of embryonic development. See bicoid, engrailed, hunchback, maternal polarity mutants, zygotic segmentation mutants.
Subjects: Genetics and Genomics.