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polyimmunoglobulin receptor


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A member of the immunoglobulin superfamily (764 aa) that is expressed on the basolateral surface of various glandular epithelia where it binds polymeric IgA and IgM; the complex is transported across the cell and secreted at the apical surface. A portion of the molecule is proteolytically cleaved and released as the secretory piece of IgA.

Subjects: Medicine and Health.


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