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pp60v-src


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The protein encoded by the oncogene of the Rous sarcoma virus (q.v.). It is a 60-kilodalton phosphoprotein, hence the pp60 in the name; the v-src indicates that it is encoded by viral gene src. The molecule is a protein kinase (q.v.) that phosphorylates tyrosine subunits in cellular proteins, particularly those that form the adhesion portions of the plasmalemma. See Chronology, 1978, Collett and Erickson; pp60c-src.

Subjects: Genetics and Genomics.


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