primer RNA

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A short RNA sequence synthesized by a primase from a template strand of DNA and serving as a required primer onto which DNA polymerase III adds deoxyribonucleotides during DNA replication. Primers are later enzymatically removed and the gaps closed by DNA polymerase I, and the remaining nicks are sealed by ligase. See primase, replication of DNA.

Subjects: Genetics and Genomics.

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