Germ cell precursors that give rise to the germ line (q.v.). In Drosophila PGCs are known as pole cells. These cells, like PGCs in many other invertebrate and vertebrate species, arise during early zygotic divisions, contain the germ plasm (q.v.), and actively migrate to their final location in the somatic component of the gonad. See pole cell.
Subjects: Genetics and Genomics — Medicine and Health.