Overview

pro-opiomelanocortin


Show Summary Details

Quick Reference

(POMC)

A polyprotein (241 aa) that is converted by serine peptidases (prohormone convertases) into several different hormones including adrenocorticotropin (ACTH), β-*lipotropin (β-LPH), corticotropin-like intermediate lobe peptide (CLIP), γ-LPH, α-melanotropin (α-MSH, α-*melanocyte-stimulating hormone), β-endorphin, γ-MSH, and β-MSH. Mutations in the gene can cause a variety of disorders, since point mutations may affect the cleavage sites for some derived hormones but not others.

Subjects: Chemistry — Medicine and Health.


Reference entries

See all related reference entries in Oxford Index »


Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.