prostaglandin-I synthase

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EC; other name: prostacyclin synthase; an enzyme that catalyses the conversion of (5Z,13E)‐(15S)‐9α,11α‐epidioxy‐15‐hydroxyprosta‐5,13‐dienoate to (5Z,13E)‐(15S)‐6,9α‐epoxy‐11α,15‐dihydroxyprosta‐5,13‐dienoate (PGI2, prostacyclin). This is a heme‐thiolate protein.

Subjects: Chemistry.

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