A variety of endogenous inhibitors that regulate the activity of peptidases. An antileukoprotease that inhibits neutrophil lysosomal elastase and cathepsin G is found in seminal fluid (human seminal plasma inhibitor-I, HUSI-I, 138 aa) and in various mucous secretions (secretory leucocyte protease inhibitor). Protease inhibitors have become the casual name for antiviral drugs. See alpha-1-antitrypsin; alpha-2-macroglobulin; serpins.
Subjects: Medicine and Health.