Overview

protein binding


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The attachment of molecules of a drug in the bloodstream to molecules of protein, especially albumin, effectively inactivating the drug by fixing it to a molecule that is too large to reach the target receptor sites. A dynamic equilibrium usually arises in which a portion of the drug is bound and a portion remains in the free form, the strength of the binding determining the quantity of the drug available in its active free form.

Subjects: Psychology.


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