protein kinase

Show Summary Details

Quick Reference

An enzyme that catalyses the transfer of a phosphate group from ATP to a specific amino acid residue of an intracellular protein (usually serine, threonine, or tyrosine), thereby affecting the biological activity of the protein. Protein kinase inhibitors are drugs that block the action of protein kinases in tumour cells and are used in the treatment of cancer. They include sorafenib, sunitinib, and temsirolimus. See also tyrosine kinase inhibitor.

Subjects: Science and Mathematics — Medicine and Health.

Reference entries

See all related reference entries in Oxford Index »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.