Overview

protocadherin 15


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A cadherin that is expressed in stereocilia of the inner ear and in retinal photoreceptors. Together with cadherin 23 (otocadherin) forms tip links, extracellular filaments that connect the stereocilia and are thought to gate the mechanoelectrical transduction channel. Mutations cause Usher's syndrome (type1F).

Subjects: Medicine and Health.


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