pulsed-field gradient gel electrophoresis

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A technique for separating DNA molecules by subjecting them to alternately pulsed, perpendicularly oriented electrical fields. The technique has allowed separation of the yeast genome into a series of molecules that ranged in weight between 40 and 1800 kilobases and represent intact chromosomes. See Chronology, 1984, Schwartz and Cantor.

Subjects: Genetics and Genomics.

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