pyruvate decarboxylase kinase

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or pyruvate dehydrogenase kinase a subunit of the mammalian pyruvate dehydrogenase complex. It phosphorylates three serine residues on pyruvate dehydrogenase (lipoamide) resulting in loss of activity, and is stimulated by elevated levels of acetyl‐CoA and NADH.


Subjects: Chemistry.

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