Overview

-phosphatase


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EC 3.1.3.43; an enzyme that catalyses the hydrolysis of phosphate from [pyruvate dehydrogenase (lipoamide)] phosphate. This hydrolysis activates the enzyme activity. Enzyme deficiency leads to inactivation of the α subunit of the appropriate dehydrogenase and consequent lactic acidosis.

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Subjects: Chemistry.


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