Overview

quinolinic acid


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An endogenous NMDA receptor agonist and neurotoxin produced in the kynurenine pathway. May be responsible for the pathogenesis of several major neuroinflammatory diseases, particularly AIDS dementia.

http://www.jneuroinflammation.com/content/2/1/16 Article in the Journal of Neuroinflammation (2005).

Subjects: Chemistry — Medicine and Health.


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