A chromosome orientation sometimes observed in interphase nuclei where centromeres are grouped near one pole and the telomeres all point toward the opposite pole. The arrangement has been interpreted to mean that centromeres and telomeres attach to opposite sides of the nuclear lamina. The orientation is named after C. Rabl, who first described the phenomenon in 1885. See Drosophila salivary gland chromosomes, lamins.
Subjects: Genetics and Genomics.