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rad proteins


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'rad proteins' can also refer to...

rad proteins

Interaction of human recombination proteins Rad51 and Rad54

SUMO modification of Rad22, the Schizosaccharomyces pombe homologue of the recombination protein Rad52

An archaeal Rad54 protein remodels DNA and stimulates DNA strand exchange by RadA

Domain mapping of the Rad51 paralog protein complexes

Interaction of p53 with the Human Rad51 Protein

Characterization of Schizosaccharomyces pombe Rad2 protein, a FEN-1 homolog

Roles of Rad23 protein in yeast nucleotide excision repair

Interaction of human Rad51 recombination protein with single-stranded DNA binding protein, RPA

Preferential binding to branched DNA strands and strand‐annealing activity of the human Rad51B, Rad51C, Rad51D and Xrcc2 protein complex

Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells

Regulation of NEIL1 protein abundance by RAD9 is important for efficient base excision repair

Bypass of heterology during strand transfer by Saccharomyces cerevisiae Rad51 protein

RadA protein from Archaeoglobus fulgidus forms rings, nucleoprotein filaments and catalyses homologous recombination

The checkpoint Saccharomyces cerevisiae Rad9 protein contains a tandem tudor domain that recognizes DNA

Multiple start codons and phosphorylation result in discrete Rad52 protein species

A Novel Nucleic Acid-Binding Protein That Interacts with Human Rad51 Recombinase

Dimerization of the Rad50 protein is independent of the conserved hook domain

Loop 2 in Saccharomyces cerevisiae Rad51 protein regulates filament formation and ATPase activity

 

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A range of proteins involved in DNA repair. The rad proteins in yeast were originally identified as products of genes that were very sensitive to X-irradiation and were involved in mitotic and meiotic recombination and mating-type switching. Subsequently human homologues of many of these proteins have been identified. The homologues of yeast RAD23, HHR23A and -B, interact with the product of the xeroderma pigmentosum gene to form a nucleotide excision repair complex. Rad51 (339 aa) is involved (together with the product of a related gene, dmc1) in the repair of double-strand breaks. Mutations to RAD51 modify susceptibility to breast carcinoma. Various others are known, and defects in DNA repair systems are usually associated with tumour susceptibility. See RAD21.

Subjects: Medicine and Health.


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