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RECQ-like helicases


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Human homologues of the E. coli RECQ helicase that is involved in mismatch repair. Five are known: the RECQL2 gene is defective in Werner's syndrome, RECQL3 in Bloom's syndrome, and RECQL4 in Rothmund–Thomson syndrome. Mutations in RECQL1 and RECQL5 are not associated with known disorders.

Subjects: Medicine and Health.


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