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n. (in transplantation) the destruction by immune mechanisms of a tissue grafted from another individual. Antibodies, complement, clotting factors, and platelets are involved in the failure of the graft to survive. Allograft rejection is a vigorous response that can be modified by drugs (such as ciclosporin and corticosteroids) and antibodies against T cells; xenograft rejection is an acute response that is at present beyond therapeutic control.

Subjects: Medicine and Health.

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