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One of the *‘fused’ gene family of proteins (784 aa) that is associated with cytokeratin intermediate filaments and partly crosslinked to the cell envelope of keratinocytes. Has calcium-binding EF-hands of the S100 type. Expressed throughout the epidermis but at higher levels in the acrosyringium, the inner hair root sheath, and the filiform papilli of the tongue.

Subjects: Medicine and Health.

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