Overview

ribavirin


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A prodrug that is metabolically activated to generate a guanoside analogue that inhibits inosine monophosphate dehydrogenase and blocks the replication of various RNA and DNA viruses. Used to treat hepatitis C infections. TNs Copegus, Rebetol, Ribasphere, Vilona, Virazole.

Subjects: Clinical Pharmacology and Therapeutics.


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