An autosomal dominant disorder of morphogenesis in which there is abnormal development of the anterior segment of the eye, causing glaucoma in many cases. Other developmental defects may also occur. Rieger's syndrome type 1 is caused by mutation in the paired homeobox transcription factor ptx2, but other types have been distinguished.
http://www.whonamedit.com/synd.cfm/1283.html Entry for Rieger's syndrome on Who Named It? website.
Subjects: Medicine and Health.