Robertsonian translocation

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A nonreciprocal chromosomal translocation in which the long arms of two nonhomologous acrocentric chromosomes are attached to a single centromere and the short arms to another. The two short arms often disappear at a subsequent division. Robertsonian translocations in humans are confined to the acrocentric chromosomes 13, 14, 15, 21, and 22, the short arms of which have no essential genetic material.

Subjects: Medicine and Health — Chemistry.

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