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A multiprotein complex that activates transcription by remodelling chromatin and mediating histone acetylation and deubiquitination and is required for transcription of a subset of RNA polymerase II-dependent genes. The SAGA complex is recruited to specific gene promoters by activators such as myc and is required for nuclear receptor-mediated transactivation. Components include ataxin-7-like protein 3.

Subjects: Medicine and Health — Chemistry.

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