Overview

sarcoglycan


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'sarcoglycan' can also refer to...

sarcoglycan

sarcoglycans

ζ-Sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy

ε-Sarcoglycan compensates for lack of α-sarcoglycan in a mouse model of limb-girdle muscular dystrophy

Loss of the Sarcoglycan Complex and Sarcospan Leads to Muscular Dystrophy in β-Sarcoglycan-Deficient Mice

Decrease in sarcoglycans and dystrophin in failing heart following acute myocardial infarction

Genomic deletion size at the epsilon-sarcoglycan locus determines the clinical phenotype

Combined deficiency of alpha and epsilon sarcoglycan disrupts the cardiac dystrophin complex

Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle

Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants

Mannosidase I inhibition rescues the human α-sarcoglycan R77C recurrent mutation

Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx mice

Mutations That Disrupt the Carboxyl-Terminus of γ-Sarcoglycan Cause Muscular Dystrophy

The Sarcoglycan Complex in the Six Autosomal Recessive Limb-Girdle Muscular Dystrophies

Molecular and genetic characterization of sarcospan: insights into sarcoglycan–sarcospan interactions

A sarcoglycan–dystroglycan complex anchors Dp116 and utrophin in the peripheral nervous system

Myoclonus, Motor Deficits, Alterations in Emotional Responses and Monoamine Metabolism in ε-Sarcoglycan Deficient Mice

Collagen VI deficiency reduces muscle pathology, but does not improve muscle function, in the γ-sarcoglycan-null mouse

Steroid treatment causes deterioration of myocardial function in the δ-sarcoglycan-deficient mouse model for dilated cardiomyopathy

 

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A family of transmembrane proteins involved in the dystrophin-associated protein complex and that, together with dystrophin, dystroglycans, and syntrophins, link the contractile system of muscle to extracellular matrix. At least six sarcoglycans are known including α-sarcoglycan (50DAG, A2, adhalin, 387 aa), β-sarcoglycan (43DAG; A3b), and γ-sarcoglycan (35DAG; A4). Mutations in sarcoglycan genes are responsible for some forms of muscular dystrophy.

Subjects: Chemistry — Medicine and Health.


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