'sedlin' can also refer to...


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A widely expressed and conserved protein (140 aa) probably involved in transport from the endoplasmic reticulum to Golgi. Mutations in the encoding gene cause spondyloepiphyseal dysplasia tarda, a progressive skeletal disorder which mainly involves vertebral bodies and hips. The intracellular chloride channel protein CLIC1 has been shown to associate with sedlin by yeast two-hybrid screening.

Subjects: Medicine and Health.

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