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'semaphorin' can also refer to...





Integration of Opposing Semaphorin Guidance Cues in Cortical Axons

Semaphorin 5B Is a Novel Inhibitory Cue for Corticofugal Axons

Axonal Surface Molecules Act in Combination with Semaphorin 3A during the Establishment of Corticothalamic Projections

Semaphorin 3A and 3F: key players in myelin repair in multiple sclerosis?

Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system

Anti-Semaphorin 3A neutralization monoclonal antibody prevents sepsis development in lipopolysaccharide-treated mice

Functional Interaction between Matrix Metalloproteinase-3 and Semaphorin-3C during Cortical Axonal Growth and Guidance


Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes

The Guidance Molecule Semaphorin3A is Differentially Involved in the Arealization of the Mouse and Primate Neocortex

SEMA3A deletion in a family with Kallmann syndrome validates the role of semaphorin 3A in human puberty and olfactory system development

Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility

Interactions of the G quartet forming semaphorin 3F RNA with the RGG box domain of the fragile X protein family

Repulsive guidance cue semaphorin 3A in urine predicts the progression of acute kidney injury in adult patients from a mixed intensive care unit

NMDA Receptor Hypofunction Induces Dysfunctions of Energy Metabolism And Semaphorin Signaling in Rats: A Synaptic Proteome Study


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One of a class of proteins that act as guidance molecules during the development of nerve cells, immune cells, blood vessels, bone, and other tissues. There are several classes, some occurring in invertebrates and others in vertebrates; some semaphorins are secreted by cells, whereas others remain bound to the plasma membrane. However, all semaphorin molecules have a characteristic region called a sema domain. Class 3 semaphorins act as short-range cues to guide the growth cone at the tip of elongating nerve fibres along appropriate pathways through tissue. They may either attract the growth cone or repel it, depending on the particular semaphorin and the type of nerve cell. The action of semaphorins is effected by binding to any of various cell surface receptors.

Subjects: Chemistry.

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