Overview

SINE


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(short interspersed element)

Any of a class of dispersed moderately repetitive DNA found in eukaryotes, consisting of numerous copies (>105) of relatively short (<500 bp) sequences scattered throughout the genome. SINEs are not translated into proteins, occur mostly in introns, and are nonautonomous retrotransposons, which require a reverse transcriptase from another source (probably a LINE) in order to replicate via an RNA intermediate. The most notable example in humans and other primates is the Alu family.

Subjects: Chemistry.


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