short QT syndrome

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A disorder of potassium channels in which the QT interval in the cardiac cycle is short and there can be paroxysmal atrial fibrillation and sudden cardiac failure. Short QT syndrome-1 (SQT1) is caused by mutation in the KCNH2 gene (hERG that encodes a voltage-sensitive potassium channel); SQT2 by mutation in the KCNQ1 gene for the shaker-related subfamily of potassium channels which is also associated with long QT syndrome, and SQT3 by mutation in the KCNJ2 gene (Kir2.1).

Subjects: Medicine and Health.

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