Overview

shotgun sequencing


Related Overviews

 

More Like This

Show all results sharing this subject:

  • Genetics and Genomics

GO

Show Summary Details

Quick Reference

A strategy for sequencing large DNA fragments or entire genomes based on sequencing and ordering smaller fragments obtained by shotgun cloning. It relies primarily on computational power to assemble the numerous sequence reads of cloned fragments into a whole-genome sequence. By sidestepping the laborious phase of constructing physical maps of clones, shotgun sequencing is potentially faster than other approaches. It was employed by US geneticist Craig Venter's Celera Genomics company to produce a draft sequence of the human genome, from some 27 million different reads, in just three years.

Subjects: Genetics and Genomics.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.