Overview

sialyl Lewisx


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An important blood group antigen (sLex, CD15s), a tetrasaccharide that is usually attached to O-glycans on the cell surface (the sialylated form of CD15). It is the ligand to which selectins bind and is expressed on neutrophils, basophils, and monocytes; some lymphocytes; and high endothelial venules (HEV). Leucocyte adhesion deficiency type II is caused by the absence of sialyl Lewisx.

Subjects: Medicine and Health.


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