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sister chromatid cohesion


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Cohesion between the two chromatids formed from each chromosome during the S phase of the cell cycle (q.v.). The evolutionarily conserved multiprotein complex cohesin (q.v.) is the primary effector of sister chromatid cohesion in all eukaryotes. This cohesion ensures that the two chromatids attach to microtubules with opposite orientations, which is a precondition for each being drawn subsequently toward the opposite pole of the dividing cell. See chromatid, microtubules, separase.

Subjects: Genetics and Genomics.


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