Overview

site-specific recombination


'site-specific recombination' can also refer to...

site-specific recombination

site-specific recombination

site-specific recombination

The site-specific recombination system of actinophage TG1

Cre-mediated somatic site-specific recombination in mice

Controlling gene expression in yeast by inducible site-specific recombination

mwr Xer site-specific recombination is hypersensitive to DNA supercoiling

Production of unmarked mutations in mycobacteria using site-specific recombination

TangleSolve: topological analysis of site-specific recombination

SeLOX—a locus of recombination site search tool for the detection and directed evolution of site-specific recombination systems

Site-specific Recombination by the β Protein from the Streptococcal Plasmid pSM19035: Minimal Recombination Sequences and Crossing over Site

Site-specific recombination in Gram-positive theta-replicating plasmids

Stoichiometric incorporation of base substitutions at specific sites in supercoiled DNA and supercoiled recombination intermediates

Rapid metabolic pathway assembly and modification using serine integrase site-specific recombination

Regulation of site‐specific recombination by the C‐terminus of λ integrase

Synapsis and DNA cleavage in ϕC31 integrase‐mediated site‐specific recombination

Different Thermostabilities of FLP and Cre Recombinases: Implications for Applied Site-Specific Recombination

Sequence specificity of illegitimate plasmid recombination in Bacillus subtilis: Possible recognition sites for DNA topoisomerase I

Microinjection of Cre recombinase RNA induces site-specific recombination of a transgene in mouse oocytes

 

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A type of recombination catalyzed by a site-specific recombinase (q.v.), in which there is exchange of genetic material between two short, defined DNA segments containing only a small region of homology. This process involves breakage and reformation of specific phosphodiester bonds within the DNA targets, and does not require DNA synthesis or energy from a nucleotide cofactor. Recombination between inverted repeats results in inversion of a DNA segment, between repeat sequences on two DNA molecules in their cointegration, and between repeats on one DNA molecule in the excision of a DNA segment. The integration of lambda phage into the bacterial genome and its excision, and FLP/FRT recombination (q.v.), are examples of processes involving site-specific recombination. Compare with homologous recombination.

Subjects: Genetics and Genomics.


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