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Structural, Expression and Interaction Analysis of Rice SKP1-Like Genes

Expression and Interaction Analysis of Arabidopsis Skp1-Related Genes

Analysis of Skp1 glycosylation and nuclear enrichment in Dictyostelium

Risk Factors of Surgical Site Infections after Simultaneous Kidney Pancreas (SKP) Transplantation

p27 and Skp2 immunoreactivity and its clinical significance with endocrine and chemo-endocrine treatments in node-negative early breast cancer

Biphasic effect of p21Cip1 on smooth muscle cell proliferation: Role of PI 3-kinase and Skp2-mediated degradation

Pollen-Specific SKP1-Like Proteins are Components of Functional SCF Complexes and Essential for Lily Pollen Tube Elongation

Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase

Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo

Complex glycosylation of Skp1 in Dictyostelium: implications for the modification of other eukaryotic cytoplasmic and nuclear proteins

Highly Heterogeneous Rates of Evolution in the SKP1 Gene Family in Plants and Animals: Functional and Evolutionary Implications

Downregulation of SKP2 in Papillary Thyroid Cancer Acts Synergistically With TRAIL on Inducing Apoptosis via ROS

SKP2 siRNA inhibits the degradation of P27kip1 and down-regulates the expression of MRP in HL-60/A cells

Decreased level of the cell cycle regulator p27 and increased level of its ubiquitin ligase Skp2 in endometrial carcinoma but not in normal secretory or in hyperstimulated endometrium


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Proteins associated with the CDK2/cyclin A kinase complex (S-phase kinase-associated proteins) involved in regulating cell cycle progression; the complex includes a 19-kDa protein (p19, Skp1, 163 aa) and a 45-kDa protein (p45, Skp2, 424 aa). Skp1 is also a component of the SCF (Skp1-*cullin- F-box) ubiquitin ligase complex, in which Skp2 is also involved. The SCF complex regulates the function of NFκB. Skp2 can deregulate growth in vivo and may be involved in the pathogenesis of lymphomas.

Subjects: Medicine and Health.

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