Overview

SUMO


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(small ubiquitin-related modifier)

Any of a family of proteins with structural similarity to ubiquitin that are attached to other proteins within cells and modify their function or change their cellular location. Attachment of SUMO – SUMOylation – occurs chiefly in the nucleus as a post-translational modification and generally prolongs a protein's life. It can, for example, determine how a protein controls transcription or whether it moves from the nucleus to the cytosol.

Subjects: Chemistry.


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